Solosec ® (secnidazole) 2g oral granules is a 5-nitroimidazole antimicrobial agent indicated for the treatment of BV in adult women. Pharmacists are ideally positioned to answer questions, educate patients, and offer support to patients prescribed Solosec ® for BV. 6 The recommended dosage of Solosec ® is a single 2-gram packet of granules taken once orally. 6 In in vitro studies, Solosec ® had no effect on the activity of aldehyde dehydrogenase, an enzyme involved in alcohol metabolism. Solosec ® can be coadministered with combination oral contraceptives (such as combination ethinyl estradiol/norethindrone) and has no alcohol restriction. Solosec ® (secnidazole) is a BV treatment that is administered orally as a single dose. Some topical BV-indicated medications are oil-based and may compromise latex condoms or diaphragms. 5 Furthermore, the application of gels or creams may be messy and interfere with daily activities, limiting their use. 4 Commonly reported reasons for nonadherence include forgetting to take or administer a dose and wanting to consume alcohol while on medication. 3 Adherence rates for 5- and 7-day treatments may be as low as 50%. The route of administration, cost, adverse reactions, and treatment duration of these medications can impact patient adherence. Treatment for BV requires prescription medication. 1 Evidence from a systematic review and meta-analysis indicate that the prevalence of BV among the general population of reproductive-age women in North America is 27.4%. 
The replacement of hydrogen peroxide- producing bacteria in the vagina with high concentrations of anaerobic bacteria and other organisms leads to the development of BV. 1īV is a clinical syndrome resulting from an imbalance of bacteria in the vagina.
1 Bacterial vaginosis (BV) is one such infection, and some current treatments for BV require that patients use additional or alternative birth control, avoid alcohol, or take the treatment for several days.
Bv medication full#
Please see full prescribing information for Solosec ® (secnidazole).Ī vaginal infection characterized by discharge, itch, or odor will affect most women at some point during their lives. This article is sponsored by Lupin Pharmaceuticals, Inc.
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